Image 01

TobaccoReviews

Cigarettes Tobacco Reviews and News

Posts Tagged ‘heavy smokers’

Sex Hormone Levels Higher in Heavy Smokers

Thursday, September 1st, 2011

discount cigaronne cigarettesA recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) found that postmenopausal women who smoke Cigaronne cigarettes have higher androgen and estrogen levels than non-smoking women, with sex hormone levels being highest in heavy smokers.

Previous studies have shown that high levels of estrogens and androgens are potential risk factors for breast and endometrial cancer as well as type 2 diabetes. Cigarette smoking is a well established risk factor for chronic diseases such as cancer, cardiovascular disease and diabetes, but earlier studies examining the relationship between smoking and sex hormone levels have yielded inconsistent results. This new cross-sectional study in a population-based sample of postmenopausal women suggests that sex hormones may provide one plausible mechanism through which cigarette smoking influences chronic disease risk.

“The observed increase in sex hormone levels with cigarette use suggests that tobacco smoke, apart from its direct toxic and carcinogenic effects, may also influence chronic disease risk through hormonal mechanisms,” said Judith Brand, MSc, of University Medical Center Utrecht in The Netherlands and lead author of the study. “The good news is that the effect of cigarette smoking appears reversible, as an almost immediate reduction in sex hormone levels was seen in women who quit using cigarettes.”

In this study, researchers examined blood samples from 2,030 postmenopausal women aged 55-81 years. Study participants were categorized as ‘current’, ‘former’ or ‘never’ smokers based on their responses to questions regarding cigarette use. Researchers found that study participants who were ‘current’ smokers had higher circulating levels of androgens and estrogens, while ‘former’ smokers who had quit within 1-2 years had sex hormone levels the same as ‘never’ smokers.

“Obviously, quitting smoking has major health benefits such as prevention of cancer, respiratory and heart diseases,” said Brand. “Our research suggests that smoking cessation may have additional effects by modifying hormone-related disease risks, but this was not the subject of the present study and requires further investigation.”

Heavy Cigarette Smoking On the Decline

Monday, August 8th, 2011

best karelia cigarettesA recent report from researchers at the University of California at San Diego has revealed that the habit of smoking Karelia cigarettes at least one pack (20 cigarettes) a day has severely declined over the last fifty years. Investigators observed that the rate of decline was particularly noteworthy in California, where lung cancer rates also fell in proportion to the reduction in smoking rates.

The data and the corresponding interpretation of the study were printed in the Journal of the American Medical Association’s March 2011 issue.

The UCSD study showed how much smoking has declined since the early 1960s. According to reports, more than fifty percent of all adult smokers in the US smoked at least one pack per day. That number fell to just over forty percent by 2007. “Moderate” smoking (10 to 20 cigarettes a day) rates also fell. In California, the number of moderate smokers fell from 11.1 percent of all adults in 1965, down to 3.4 percent in 2007. In other states, the number fell from 10.5 percent of all adults down to 5.4 percent.

The study credits much of the decline to smoking education programs. In 1964, the US Surgeon General released the first major findings on the correlation between cigarette smoking and lung cancer. Two years later, the Food and Drug Administration required mandatory warning labels on all cigarette packaging. Today, most cigarette packs and cartons carry warning labels, including warnings about how smoking can complicate pregnancy and lead to low birth rates in pregnant women who smoke.

Another factor attributed to the reduction in smoking rates is the development in new technologies to combat nicotine addiction. One of the primary reasons that smokers find quitting so difficult is the intense nicotine addiction that smoking brings. The invention of nicotine patches, lozenges and gums as part of a smoking cessation program has helped millions of smokers quit the habit over the last twenty years.

In addition to federal mandates requiring the addition of warning labels to cigarette packaging, many state and municipal jurisdictions created anti-smoking laws and ordinances. Several states added higher taxes to cigarettes, with California among the first to enact such statutes. Also, many cities passed local laws prohibiting smoking in bars, restaurants and public buildings.

Public awareness campaigns, such as those conducted by the American Heart Association, the American Lung Association and the American Cancer Society, also helped bring the issues of cigarette smoking to the attention of the American public. The campaigns highlighted many of the dangers that surround cigarette smoking, including lung cancer, throat cancer and emphysema.

As California took the lead in many of the anti-smoking efforts, the study also showed how lung cancer incidence rates declined in the state well before other states saw the same results. Deaths from lung cancer peaked in 1987 in California, with 109 per 100,000. The death rate fell to 77 per 100,000 in 2007. In other states, the lung cancer death rate peaked in 1993 at 117 per 100,000 and fell to 102 per 100,000 in 2007.

Heavy Smokers, Smoking Struggle

Wednesday, August 3rd, 2011

cheap pall mall cigarettes onlineA new study suggests another reason for why people struggle to quit smoking – a habit that kills tens of thousands of Canadians each year. People who smoke a pack or more of cigarettes daily had elevated levels of a protein known as monoamine oxidase in their brains in the early stages of abstaining from smoking Pall Mall cigarettes, a Canadian study reported Tuesday.

That chemical is found at high levels in people with clinical depression.

The Toronto-based Centre for Addiction and Mental Health discovered the protein by doing brain scans of heavy smokers eight hours after having their last cigarette.

These smokers also reported increased feelings of sadness in questionnaires done as part of the study.

Monoamine oxidase is a protein that feeds on other chemicals in the brain, such as serotonin, which helps regulate mood.

While past research has shown elevated levels of monoamine oxidase in people diagnosed with clinical depression, creators of this study said it was the first time it was studied in connection to cigarette withdrawal.

The researchers said such findings could explain why smokers are at a higher risk of suffering from depression – almost twice that of the general population, according to Jeffrey Meyer, a senior scientist with the Centre for Addiction who led the study.

The findings were based on brain scans of 48 subjects, half of whom were non-smokers and the smoking factions were evenly divided between those who smoke 15 to 24 cigarettes a day and those who smoke 25 or more.

Those in the heavy-smoking category saw their monoamine oxidase levels rise about 25 per cent eight hours after having their last cigarette. No significant change was seen among the more moderate smokers.

It provides another possible reason why quitting smoking is so difficult – creating unpleasant emotions among those attempting to stop. Meyer said the effect is completely separate from nicotine addiction.

The study said a key factor in the findings could be the presence of a substance called harman in cigarette smoke. This suppresses monoamine oxidase in the brain of a person who has just had a cigarette. The study shows that this substance rebounds to higher-than normal levels in heavy smokers in withdrawal.

“The more we understand about mechanisms, the more sophisticated prevention strategies we can come up with,” Meyer said.

For example, he suggested efforts could be made to develop drugs that suppress monoamine oxidase in people who are trying to stop smoking.